sábado, 18 de agosto de 2012


Surprising finding: Tree's leaves genetically different from its roots


Black cottonwood trees (Populus trichocarpa) can clone themselves to produce offspring that are connected to their parents by the same root system. Now, after the first genome-wide analysis of a tree, it turns out that the connected clones have many genetic differences, even between tissues from the top and bottom of a single tree. The variation within a tree is as great as the variation across unrelated trees. Such somatic mutations — those that occur in cells other than sperm or eggs — are familiar to horticulturalists, who have long bred new plant varieties by grafting mutant branches onto ‘normal’ stocks. But until now, no one has catalogued the total number of somatic mutations in an individual plant.

In one tree, the top buds of the parent and offspring were genetically closer to each other than to their respective roots or lower branches. In another tree, the top bud was closer to the reference cottonwood genome than to any of the other tissues from the same individual.The tissue-specific mutations affected mainly genes involved in cell death, immune responses, metabolism, DNA binding and cell communication. Olds think that this may be because many of the mutations are harmful, and the tree reacts by destroying the mutated tissues or altering its metabolic pathways and the way it controls its genes, which leads to further mutations.

The findings have parallels to cancer studies, which have recently shown that separate parts of the same tumor can evolve independently and build up distinct genetic mutations, meaning that single biopsies give only a narrow view of the tumor’s diversity.


Human cycles: History as science



For the past 15 years, Turchin has been taking the mathematical techniques that once allowed him to track predator–prey cycles in forest ecosystems, and applying them to human history. He has analysed historical records on economic activity, demographic trends and outbursts of violence in the United States, and has come to the conclusion that a new wave of internal strife is already on its way1. The peak should occur in about 2020, he says, and will probably be at least as high as the one in around 1970. “I hope it won't be as bad as 1870,” he adds.

Human cycles: History as science
Laura Spinney
Nature 488, 24–26 (02 August 2012) http://dx.doi.org/10.1038/488024a


Inescapable Pull
Black holes, once the preserve of theory and science fiction, are well-established inhabitants of the universe. Observations of the motions of stars orbiting the center of the Milky Way have proved beyond doubt that a black hole 4 million times as massive as the Sun resides there. Many other galaxies are thought to host similarly heavy or even heavier black holes at their centers. Scattered out beyond the center, there are thought to be millions of lighter, stellar-mass black holes, produced when the most massive stars collapse in on themselves at the end of their lives. This week, Science explores the current state of understanding of black holes with a series of Perspectives and Reviews.

Inescapable Pull
Maria Cruz
Science 3 August 2012:
Vol. 337 no. 6094 p. 535
http://dx.doi.org/10.1126/science.337.6094.535


Measuring the Complexity of Ultra-Large-Scale Evolutionary Systems
Ultra-large scale (ULS) systems are becoming pervasive. They are inherently complex, which makes their design and control a challenge for traditional methods. Here we propose the design and analysis of ULS systems using measures of complexity, emergence, self-organization, and homeostasis based on information theory. We evaluate the proposal with a ULS computing system provided with genetic adaptation mechanisms. We show the evolution of the system with stable and also changing workload, using different fitness functions. When the adaptive plan forces the system to converge to a predefined performance level, the nodes may result in highly unstable configurations, that correspond to a high variance in time of the measured complexity. Conversely, if the adaptive plan is less "aggressive", the system may be more stable, but the optimal performance may not be achieved.

Measuring the Complexity of Ultra-Large-Scale Evolutionary Systems
Michele Amoretti, Carlos Gershenson


Some Computational Aspects of Essential Properties of Evolution and Life
While evolution has inspired algorithmic methods of heuristic optimisation, little has been done in the way of using concepts of computation to advance our understanding of salient aspects of biological phenomena. We argue that under reasonable assumptions, interesting conclusions can be drawn that are of relevance to behavioural evolution. We will focus on two important features of life--robustness and fitness--which, we will argue, are related to algorithmic probability and to the thermodynamics of computation, disciplines that may be capable of modelling key features of living organisms, and which can be used in formulating new algorithms of evolutionary computation.

Some Computational Aspects of Essential Properties of Evolution and Life
Hector Zenil, James A.R. Marshall


Why We Lie
 

Over the past decade or so, my colleagues and I have taken a close look at why people cheat, using a variety of experiments and looking at a panoply of unique data sets—from insurance claims to employment histories to the treatment records of doctors and dentists. What we have found, in a nutshell: Everybody has the capacity to be dishonest, and almost everybody cheats—just by a little. Except for a few outliers at the top and bottom, the behavior of almost everyone is driven by two opposing motivations. On the one hand, we want to benefit from cheating and get as much money and glory as possible; on the other hand, we want to view ourselves as honest, honorable people. Sadly, it is this kind of small-scale mass cheating, not the high-profile cases, that is most corrosive to society.

Introducing the Computable Universe
Some contemporary views of the universe assume information and computation to be key in understanding and explaining the basic structure underpinning physical reality. We introduce the Computable Universe exploring some of the basic arguments giving foundation to these visions. We will focus on the algorithmic and quantum aspects, and how these may fit and support the computable universe hypothesis.

Introducing the Computable Universe
Hector Zenil

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