Self-extinction through optimizing selection

Evolutionary suicide is a process in which selection drives a viable population to extinction. So far, such selection-driven self-extinction has been demonstrated in models with frequency-dependent selection.

See it on Scoop.it, via Papers

Constraint and Contingency in Multifunctional Gene Regulatory Circuits

Many essential biological processes, ranging from embryonic patterning to circadian rhythms, are driven by gene regulatory circuits, which comprise small sets of genes that turn each other on or off to form a distinct pattern of gene expression. Gene regulatory circuits often have multiple functions. This means that they can form different gene expression patterns at different times or in different tissues. We know little about multifunctional gene regulatory circuits. For example, we do not know how multifunctionality constrains the evolution of such circuits, how many circuits exist that have a given number of functions, and whether tradeoffs exist between multifunctionality and the robustness of a circuit to mutation. Because it is not currently possible to answer these questions experimentally, we use a computational model to exhaustively enumerate millions of regulatory circuits and all their possible functions, thereby providing the first comprehensive study of multifunctionality in model regulatory circuits. Our results highlight limits of circuit designability that are relevant to both systems biologists and synthetic biologists.

 

Payne JL, Wagner A (2013) Constraint and Contingency in Multifunctional Gene Regulatory Circuits. PLoS Comput Biol 9(6): e1003071.http://dx.doi.org/10.1371/journal.pcbi.1003071

Can Life Evolve from Wires and Plastic?

In a laboratory tucked away in a corner of the Cornell University campus, Hod Lipson’s robots are evolving. He has already produced a self-aware robot that is able to gather information about itself as it learns to walk.

 

Hod Lipson reports: "We wrote a trivial 10-line algorithm, ran it on big gaming simulator, put it in a big computer and waited a week. In the beginning we got piles of junk. Then we got beautiful machines. Crazy shapes. Eventually a motor connected to a wire, which caused the motor to vibrate. Then a vibrating piece of junk moved infinitely better than any other… eventually we got machines that crawl. The evolutionary algorithm came up with a design, blueprints that worked for the robot."

 

The computer-bound creature transferred from the virtual domain to our world by way of a 3D printer. And then it took its first steps. Was this arrangement of rods and wires the machine-world’s equivalent of the primordial cell? Not quite: Lipson’s robot still couldn’t operate without human intervention. ‘We had to snap in the battery,’ he told me, ‘but it was the first time evolution produced physical robots. Eventually, I want to print the wires, the batteries, everything. Then evolution will have so much freedom. Evolution will not be constrained.’

 

Not many people would call creatures bred of plastic, wires and metal beautiful. Yet to see them toddle deliberately across the laboratory floor, or bend and snap as they pick up blocks and build replicas of themselves, brings to mind the beauty of evolution and animated life.

 

One could imagine Lipson’s electronic menagerie lining the shelves at Toys R Us, if not the CIA, but they have a deeper purpose. Lipson hopes to illuminate evolution itself. Just recently, his team provided some insight into modularity—the curious phenomenon whereby biological systems are composed of discrete functional units.

 

Though inherently newsworthy, the fruits of the Creative Machines Lab are just small steps along the road towards new life. Lipson, however, maintains that some of his robots are alive in a rudimentary sense. ‘There is nothing more black or white than alive or dead,’ he said, ‘but beneath the surface it’s not simple. There is a lot of grey area in between.’

 

The robots of the Creative Machines Lab might fulfill many criteria for life, but they are not completely autonomous—not yet. They still require human handouts for replication and power. These, though, are just stumbling blocks, conditions that could be resolved some day soon—perhaps by way of a 3D printer, a ready supply of raw materials, and a human hand to flip the switch just the once.

 

According to Lipson, an evolvable system is ‘the ultimate artificial intelligence, the most hands-off AI there is, which means a double edge. All you feed it is power and computing power. It’s both scary and promising.’ What if the solution to some of our present problems requires the evolution of artificial intelligence beyond anything we can design ourselves? Could an evolvable program help to predict the emergence of new flu viruses? Could it create more efficient machines? And once a truly autonomous, evolvable robot emerges, how long before its descendants make a pilgrimage to Lipson’s lab, where their ancestor first emerged from a primordial soup of wires and plastic to take its first steps on Earth?

In the light of evolution VII: The human mental machinery

This collection of colloquium papers aims to survey what has been learned about the human “mental machinery” since Darwin's insights. The colloquium brought together leading scientists who have worked on brain and mental traits. Their 16 contributions focus the objective of better understanding human brain processes, their evolution, and their eventual shared mechanisms with other animals. The articles are grouped into three primary sections: current study of the mind/brain relationships; the primate evolutionary continuity; and the human difference: from ethics to aesthetics.

 

In the light of evolution VII: The human mental machinery
Camilo J. Cela-Conde, Raúl Gutiérrez Lombardo, John C. Avise, and Francisco J. Ayala

http://dx.doi.org/10.1073/pnas.1307207110 
PNAS June 18, 2013 vol. 110 no. Supplement 2 10339-10342

Earth is surrounded by a 'bubble' of live bacteria - at 33 000 feet

Earth’s upper atmosphere—below freezing, nearly without oxygen, flooded by UV radiation—is no place to live. But last winter, scientists from the Georgia Institute of Technology discovered that billions of bacteria actually thrive up there. Expecting only a smattering of microorganisms, the researchers flew six miles above Earth’s surface in a NASA jet plane. There, they pumped outside air through a filter to collect particles. Back on the ground, they tallied the organisms, and the count was staggering: 20 percent of what they had assumed to be just dust or other particles was alive. Earth, it seems, is surrounded by a bubble of bacteria.

 

Scientists don’t yet know what the bacteria are doing up there, but they may be essential to how the atmosphere functions, says Kostas Konstantinidis, an environmental microbiologist on the Georgia Tech team. For example, they could be responsible for recycling nutrients in the atmosphere, like they do on Earth. And similar to other particles, they could influence weather patterns by helping clouds form. However, they also may be transmitting diseases from one side of the globe to the other. The researchers found E. coli in their samples (which they think hurricanes lifted from cities), and they plan to investigate whether plagues are raining down on us. If we can find out more about the role of bacteria in the atmosphere, says Ann Womack, a microbial ecologist at the University of Oregon, scientists could even fight climate change by engineering the bacteria to break down greenhouse gases into other, less harmful compounds.